Estimating Modifying Effect of Age on Genetic and Environmental Variance Components in Twin Models
نویسندگان
چکیده
منابع مشابه
Estimating Modifying Effect of Age on Genetic and Environmental Variance Components in Twin Models.
Twin studies have been adopted for decades to disentangle the relative genetic and environmental contributions for a wide range of traits. However, heritability estimation based on the classical twin models does not take into account dynamic behavior of the variance components over age. Varying variance of the genetic component over age can imply the existence of gene-environment (G×E) interact...
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ژورنال
عنوان ژورنال: Genetics
سال: 2016
ISSN: 1943-2631
DOI: 10.1534/genetics.115.183905